Orlando, Fla.

A section of State Road 528 in Orange County has been closed after an SUV collided with box truck traveled the wrong direction, crashed, then caught on fire.

The crash happened early Thursday morning at around 2:00 am.

Florida Highway Patrol has closed the section between Dallas Boulevard and Wedgefield Drive in eastern Orange County.

Witnesses say that an SUV was traveling east in the westbound lanes when struck a vehicle then slammed into a box truck. The SUV and the box truck then burst into flames.

At least one person is dead and several others are injured.

Troopers have not said which vehicle the fatality was from or the names of the victims.

The cause of the crash is under investigation.

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